CHILDHOOD TRAUMA SUBTYPES MAY INFLUENCE THE PATTERN OF SUBSTANCE USE AND PREFERENTIAL SUBSTANCE IN MEN WITH ALCOHOL AND/OR CRACK-COPYRIGHT ADDICTION

Childhood trauma subtypes may influence the pattern of substance use and preferential substance in men with alcohol and/or crack-copyright addiction

Objective: To compare the prevalence and subtypes of Plaque LED Night Light childhood maltreatment (CM) between individuals with and without substance use disorder (SUD) and investigate the influence of different traumas on the preferential use of substances and the severity of dependence.Methods: The sample consisted of 1,040 men with SUD (alcohol

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Highly Efficient Clinical Trials Simulator (HECT): Software application for planning and simulating platform adaptive trials [version 2; peer review: 1 approved, 2 approved with reservations]

Background: Adaptive designs and platform designs are among two common clinical trial innovations that are increasingly being used to manage medical intervention portfolios and attain faster regulatory approvals.Planning of adaptive and platform trials necessitate simulations to understand how a set of adaptation rules will likely affect the proper

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